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KMID : 1149120200170020042
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Journal of the Korean Society for Psoriasis
2020 Volume.17 No. 2 p.42 ~ p.46
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A Case of Treatment with Ixekizumab for Exacerbated Psoriasis after Chemotherapy in Breast Cancer Patient
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Lee Eun-Hye
Kim Jun-Young
Jang Yong-Hyun
Lee Weon-Ju
Lee Seok-Jong
Park Kyung-Duck
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Abstract
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A 48-year-old woman, who was experienced the aggravation of psoriasis after chemotherapy, visited our medical center. She was suffered from mild psoriasis for about 20 years and it was controlled using topical steroid and vitamin D agent. Six months ago, she was diagnosed with breast cancer and received preoperative chemotherapy with doxorubicin, cyclophosphamide, docetaxel, and trastuzumab, after which extensive pruritic erythematous papules and scaly plaques developed. She did not respond to conventional treatment including oral cyclosporine. She started ixekizumab to treat aggravated psoriasis. Most of the lesions appeared to be improved after 8 injections of ixekizumab, and trastuzumab with hormonal therapy are currently being used to control breast cancer. There is some debate regarding treatment with biologics in psoriasis patients with a history of cancer due to the burden of recurrence or progression of cancer. Herein, we report a case of treatment with ixekizumab for exacerbated psoriasis after chemotherapy.
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KEYWORD
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Breast cancer, Chemotherapy, Ixekizumab, Psoriasis
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